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Confirm that the use of assessments and training is for yourselfYou are going to create a personal account. This type of account is specially designed to help you evaluate and train your cognitive skills

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For users 16 years and older. Children under 16 can use CogniFit with a parent on one of the family platforms.


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Cognitive Abilities
Internal consistency
Test-retest reliability
Divided Attention
Width of Field of View
Hand-eye Coordination
Focused Attention
Visual Scanning
Auditory Short-term Memory
Contextual Memory
Visual Short Term Memory
Short-Term Memory
Working Memory
Non-verbal Memory
Spatial Perception
Visual Perception
Auditory perception
Response Time
Processing Speed

Reliability analysis of the evaluation (Only in English)Download

Cognitive Assessment for Chemo Fog Research (CAB-CF)

Innovative neuropsychological assessment for Chemo Brain allows for a complete cognitive screening and evaluation to detect the risk index of suffering from cognitive deterioration after an oncological process.

Who is it for?

This product is for research purposes only. For more info see CogniFit Research Platform


Cognitive Assessment for Chemo Fog Research (CAB-CF)

Confirm that the use of assessments and training is for yourselfYou are going to create a personal account. This type of account is specially designed to help you evaluate and train your cognitive skills

Confirm that you want to offer training and/or cognitive assessments to your family or friends.You are going to create a family account. This account is designed to give your family members access to CogniFit evaluations and training.

Number of assessments*

* Assessment licenses can be used for any type of assessment

What is the CogniFit Chemo Brain Test?

What is the CogniFit Chemo Brain Test?

  • Evaluate the risk index of the presence of Chemo Brain
  • For adults of all ages
  • Takes about 30-40 minutes to complete
  • Reliability analysis of the evaluation - Only in English Download

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) from CogniFit is a leading professional test that uses clinical and validated tasks designed to quickly and accurately detect the presence of symptoms, traits, or dysfunctions in the cognitive processes affected by cancer treatment.

This innovative Chemo Brain test is a scientific resource that makes it possible to take a complete cognitive screening, understand cognitive strengths and weaknesses, and evaluate the risk index for the presence of Chemo Brain (or Chemo Fog). This test is suitable for people 18 years and older, like young adults, adults, or seniors who have undergone cancer treatment and may present related cognitive decline. Anyone can easily use this neuropsychological assessment battery. The results of this assessment will automatically be available after completing the test, which usually lasts about 30-40 minutes.

Cancer is one of the most devastating diseases that we have today, and the treatments for it can be aggressive for the patient. These treatment processes can noticeably weaken different cognitive skills, affecting daily life. The detection of this cognitive deterioration is an important part of the intervention and correction of this cognitive decline, and the earlier that you work to improve the skills, the better chance there is of recovering cognitive function and independence.

A clinical consultation and history, questionnaires, clinical evaluation scales, and clinical test are all effective tools for detecting certain cognitive problems, but they are able to detect the degree to which these cognitive skills are affected. A clinically validated neuropsychological assessment can help perform an exhaustive assessment of the different cognitive functions affected by cancer treatments. Note that CogniFit does not directly offer a medical diagnosis of chemo fog but the neuropsychological assessment can help perform a screening of different cognitive functions. We recommend using this Chemo Brain test to complement a professional assessment, and never to replace a clinical consultation.

Phases of this Chemo Brain Test (CAB-CF)

Phases of this Chemo Brain Test (CAB-CF)

This complete cognitive evaluation to detect Chemo Fog and Chemo Brain are made up of a questionnaire and a complete battery of neuropsychological tests. It usually takes about 30-40 minutes to complete.

Any adult who has undergone chemotherapy treatment will answer the questionnaire in order to evaluate the clinical signs and symptoms related to these cognitive alterations. After the questionnaire, a series of validated tasks presented as online games will appear on the screen for the user to complete.

Diagnostic Criteria Questionnaire

A series of simple questions designed to detect the main symptoms of Mental Fog will be presented. This questionnaire is an evaluation tool adapted to the effects of Chemo Brain.

Neuropsychological factors and cognitive profile

The CAB-CF continues with a battery of tasks aimed at evaluating the main neuropsychological factors identified in the scientific literature surrounding this disorder. The results will be compared to other users of the same age and gender.

Complete results report

After completing the Chemo Brain test, a detailed report will be available to download, where the user's risk index for Mental Fog will appear, along with a description of the warning signs, cognitive profile, and results analysis, and recommendations. These results offer valuable information to help create an appropriate support strategy.

Psychometric Results

Psychometric Results

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) from CogniFit uses patented algorithms and artificial intelligence (AI) that makes it possible to analyze thousands of variables and highlight any risk of Mental Fog with very satisfactory psychometric results.

The cognitive profile in the neuropsychological report has received high reliability, consistency, and stability ratings. The test has been validated through repeated tests and measurement processes. Transversal research designed, like the Cronbach Alpha have been followed, reaching scores of about .9, and the Test-Retest tests received scores of almost 1, which shows the high level of reliability and precision.

See validation table

Who is it for?

Who is it for?

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) can be used by adults of all ages who are receiving or have received chemotherapy.

Any individual or professional can easily use this neuropsychological assessment tool to detect the cognitive alterations caused by a cancer treatment. No specialized training or knowledge of neuroscience or technology systems is necessary to use this test. It is especially designed for:

Individual Users

Know the state of my brain, as well as my strengths or weaknesses

Using CogniFit Chemo Brain Cognitive Assessment Battery, we will be able to know the risk of suffering this consequence of chemotherapy as a cancer treatment. It will be very helpful to know if the cognitive problems we notice are normal for our age, or if they are a symptom of this problem.

Healthcare Professionals

Easily and reliably evaluate patients and offer a complete, detailed report

The neuropsychological Chemo Brain test from CogniFit makes it possible for healthcare professionals to detect, diagnose, and create an intervention for this disorder. Detecting the symptoms of Mental Fog is the first step to identifying the cognitive alterations caused by it, and creating an appropriate cognitive intervention. This powerful software allows you to study multiple variables and offer complete, personalized reports.

Families, caretakers, and individual users

Identify if a loved-one presents a risk of cognitive decline related to Mental Fog

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) is a scientific resource made up of a simple-answer questionnaire and online tasks. This makes it possible for any user, even without specialized training, to evaluate the different symptoms and neuropsychological factors that may be indicative of Chemo Fog. The comprehensive report will help identify the risk of having a cognitive disorder related to chemotherapy and outline specific guidelines for each individual case.


Measures the cognitive abilities of study participants

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) makes it possible to precisely measure a wide variety of cognitive skills. CogniFit's technology takes thousands of variables into account from the assessment activities in order to gather reliable information about the participant's cognitive state.



This online, scientifically based evaluation tool to quickly and reliably assess the symptoms, strengths, weaknesses, and cognitive processes affected by Chemo Brain has a number of advantages:


The Cognitive Assessment for Chemo Fog Patients (CAB-CF) from CogniFit is a professional resource created by specialists in cognitive alterations. The cognitive tests have been patented and clinically validated. This leading professional tool is used by the scientific community, families, universities, associations and foundations, and medical centers around the world.


Any professional or individual user can use this assessment battery for Chemo Brain. No special training or background in technology services necessary to assign and use this assessment battery, making it simple and efficient to use from home or at the office.


All of the clinical tasks are presented automatically, and are shown as simple, fun, and interactive brain games and exercises, which makes them easy to understand and fun to play, improving comprehension.


The Cognitive Assessment for Chemo Fog Patients (CAB-CF) makes it possible to provide quick and reliable information. This report is easy to understand and makes it possible to see and understand the clinical symptoms, strengths and weaknesses, and risk index for having Chemo Fog.


This powerful software allows you to analyze thousands of variables and offer specific recommendations for each user's needs and type of deterioration.

When should you use this Chemo Brain test?

When should you use this Chemo Brain test?

This assessment battery makes it possible to reliably detect the symptoms and level of cognitive deterioration related to Chemo Fog in adults and seniors.

Without the proper intervention and help, Chemo Fog may start to affect a person's professional, personal, and family areas.

Chemo Fog may cause generalized deterioration and difficulties at work or at home. We can differentiate between:

Most representative symptoms
Symptoms of Chemo Brain
Emotional Symptoms
Physical Symptoms

Symptoms of Chemo Brain

This term is used to describe the changes in memory, attention, and concentration, and the ability to do different mental tasks that are related to chemo or hormone therapy treatment for cancer. Other factors aside from medication can also play a role in these cognitive deficits, like age, gender, and the type of cancer.

Emotional Symptoms

A cancer diagnosis and its progression can cause considerable psychological distress and patients and their families. Studies show that between 25% and 50% of patients diagnosed with cancer will experience varying levels of emotional distress. Recent studies have shown that there is a higher presence of depression, anxiety, and emotional distress in cancer patients than the general population.

Physical Symptoms

Both the treatment and the disease itself can cause physical, digestive, metabolic, motor and sleep changes, as well as an alteration in how one sees their self-image. These changes may have a lesser or greater effect on the patient.







Description of the diagnostic criteria questionnaire

Description of the diagnostic criteria questionnaire

Mental Fog or Chemo Brain is characterized by a series of clinical symptoms. These indicators can help better understand the presence of this disorder, which is why the first part of the Cognitive Assessment for Chemo Fog Patients (CAB-CF) is a questionnaire that adapts to the main diagnostic symptoms of Chemo Fog for each age range.

The questions in this questionnaire are similar to what one may find in a diagnostic manual, clinical questionnaire, or scales for Chemo Fog. However, the questions have been simplified to be easily understood by any user.

Diagnostic Criteria for Chemo Brain for Adults and Seniors

Made up of a series of simple questions that can be completed by the professional responsible for the assessment or the person taking the Chemo Brain test. The questionnaire covers the following domains: Emotional symptoms (psychological distress, like anxiety or depression), Physical symptoms (changes in self-image, metabolic changes, sleep changes, fatigue, muscle pain, etc.), and Chemo Fog symptoms (problems with different cognitive skills, like memory or attention).

What cognitive skills are assessed with this Chemo Brain test?

What cognitive skills are assessed with this Chemo Brain test?

The presence of alterations in some cognitive skills may be an indicator of Chemo Brain. A general profile of the cognitive skills may help you understand the severity of the cognitive alterations caused by this disorder. The cognitive domains most altered by cancer treatment, and thus assessed in the Cognitive Assessment for Chemo Fog Patients (CAB-CF) are:

Evaluated Cognitive Domains
Cognitive Abilities


Ability to filter distractions and focus on relevant information.


8.1% above average

Focused Attention

Focused attention and Chemo Brain. Focused attention is the ability to focus attention on one target stimulus, independently of the duration. Poor attention and problems concentrating are frequent complaints of people who have undergone cancer treatment. This attention deficit influences daily life, like when reading a book, following a conversation, or watching TV.

661Your Score



Updating and Chemo Brain. Updating is the ability to supervise an action to ensure that it is being carried out using the prepared plan of action. People who have had hormone or chemotherapy may have cognitive problems when supervising their behavior, especially when dealing with a complex task or little-perceived feedback.

502Your Score



Ability to retain or manipulate new information and recover memories from the past.


8.5% above average

Short-Term Memory

Short-term memory and Chemo Brain. Short-term memory is the ability to hold onto a small amount of information over a short period of time, like when we remember the beginning of a sentence in order to make sense of the sentence as a whole. A problem in short-term memory may alter one's ability to understand what they hear or impede their ability to correctly understand the information that they receive. According to research, cancer patients have noticed an alteration in their short-term memory after treatment.

729Your Score


Working Memory

Working memory and Chemo Brain. After cancer treatment, patients often mention a decline in their working memory, which is the ability to use the information necessary to carry out complex cognitive tasks, like comprehension, learning, and reasoning. A poor working memory may cause difficulty remembering appointments or turning off the lights when leaving the house. The neurotoxicity of the medications used in oncological processes, stress, and anxiety may cause this decline in working memory.

656Your Score



Ability to efficiently carry-out precise and organized movements.


7.5% above average

Response Time

Reaction time and Chemo Brain. Reaction time is the ability to perceive, process, and respond to a simple stimulus, like answering a specific question. People who have undergone hormone or chemotherapy often talk of a "mental fog", as if they weren't able to think clearly, which manifests itself as a slow response time, as it's likely that they have more trouble forming fluid and correct responses.

558Your Score



Ability to interpret the stimuli from one's surroundings.


7.9% above average


Recognition and Chemo Brain. Recognition is the brain's ability to identify the stimuli that we have perceived before (situations, people, objects, etc.). Recognition and other visual alterations have been described as possible cognitive side effects of chemotherapy, which may affect reading, driving, or other daily tasks.

596Your Score



Ability to efficiently use (organize, relate, etc.) acquired information.


7.8% above average


Planning and Chemo Brain. Planning is the ability to mentally organize the best way to reach a certain future goal, like when you think about how to tell a story to your friends. The Chemo Fog effect described alterations in planning, which may cause problems structuring thoughts, ideas, daily activities, or any other task that requires a certain amount of planning and organization.

580Your Score


Evaluation tasks

Evaluation tasks

This multi-dimensional scientific resource uses multiple evaluation tasks. Here you can see examples:

Processing Test REST-INH

The Processing Test REST-INH was inspired by the classic Variables of Attention (TOVA) test.The task helps to perceive, process, and respond to a stimulus. Depending on the processing speed, the response time will be affected to a greater or lesser extent. It will also allow the user to ignore irrelevant or unimportant stimuli.

Recognition Test WOM-REST

The Recognition Test WOM-REST is based on the Continuous Performance Test (CTP), the Test of Memory Malingering (TOMM), the Visual Organization Task (VOT), and the Test of Variables of Attention (TOVA). The task will help evaluate the user's executive functions and understand which are their strengths and weaknesses when organizing and acting depending on the stimulus.

Equivalencies Test INH-REST

The Equivalencies Test INH-REST is based on Stroop's classic test. This test evaluates the user's capacity to discern between two tasks as the same time, focusing on the main task and ignoring the less important ones. This task will help activate two parts of the brain at the same time, developing both parts that are used in the process. As the user will have to attend to more than one stimuli at a time, the test will require concentration and focus.

Concentration Test VISMEN-PLAN

This evaluation task is inspired by the Wechsler Memory Scale (WMS) direct and indirect digits test, the classic Memory Malingering Test (TOMM) and the classic Tower of London Test (TOL), allowing to measure planning capacity, visual memory, short-term memory, response time, working memory and processing speed, among others.

Chemo Fog and The Brain

Chemo Fog and The Brain

The cognitive problems related to Mental Fog or Chemo Brain are based on determined brain alterations. Unlike other disorders, the specific brain areas affected by Chemo Fog have not been identified, but rather, damage to the brain on the whole. This is why a general division makes it possible to distinguish between the alterations in the gray matter (neural nuclei) and white matter (neural axons). Few studies have been conducted with respect to the effect that certain drugs used in cancer treatments may cause, but there are some robust conclusions.

  • Difficulty concentration and thinking clearly
  • Problems multi-tasking (doing multiple things at the same time)
  • Problems remembering words during a conversation
  • Slower processing speed when learning new things
  • Difficulty concentrating
  • Difficulty organizing oneself or feeling mentally "fuzzy"

Because of this symptomology, we can infer that some of the brain structures affected are:

1 Prefrontal Lobe

Is in charge of planning behavior and attending to various stimuli at the same time, remembering recent events, concentration, and structuring thought.

2 White Matter

White matter refers to the set of neural axons. These axons work to connect and help neurons communicate between each other, which means that the information received from one side of the brain can be transmitted to another neuron (or set of neurons) on the other side. Chemotherapy may produce a diffusion in the transmission of information from one neuron to another, which may cause slower processing speed and response time, making it more difficult to carry out daily activities.

Customer Service

Customer Service

If you have any questions about data operation, management or interpretation of our assessments, you can contact us immediately. Our team of professionals will solve your doubts and help you with anything you need.

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